AskDefine | Define phenotypic

Dictionary Definition

phenotypic adj : of or relating to or constituting a phenotype; "phenotypical profile" [syn: phenotypical]

User Contributed Dictionary



  1. Of, or relating to a phenotype.

Extensive Definition

A phenotype is any observable characteristic of an organism, such as its morphology, development, biochemical or physiological properties, or behavior. Phenotypes are influenced by a combination of genetic and environmental factors. This contrasts with the genotype of an organism - the inherited instructions it carries - which may or may not cause an observable effect on the organism. This genotype-phenotype distinction was proposed by Wilhelm Johannsen in 1911 to make clear the difference between an organism's heredity and what that heredity produces. The distinction is similar to that proposed by August Weismann, who distinguished between germ plasm (heredity) and somatic cells (the body). A more modern version is Francis Crick's Central dogma of molecular biology.
Despite its seemingly straightforward definition, the concept of the phenotype has some hidden subtleties. First, most of the molecules and structures coded by the genetic material are not visible in the appearance of an organism, yet they are observable (for example by Western blotting) and are thus part of the phenotype. Human blood groups are an example. So, by extension, the term phenotype must include characteristics that can be made visible by some technical procedure. A further, and more radical, extension would add behaviour to the phenotype since behaviours are also affected by both genotypic and environmental factors.
Second, the phenotype is not simply a product of the genotype, but is influenced by the environment to a greater or lesser extent (see also phenotypic plasticity). And, further, if the genotype is defined narrowly, then it must be remembered that not all heredity is carried by the nucleus. For example, mitochondria transmit their own DNA directly, not via the nucleus, though they divide in unison with the nucleus.
The phenotype is composed of traits or characteristics . Some phenotypes are controlled entirely by the individual's genes. Others are controlled by genes but are significantly affected by extragenetic or environmental factors. Almost all humans inherit the capacity to speak and understand language, but which language they learn is entirely an environmental matter.

Phenotypic variation

Phenotypic variation (due to underlying heritable genetic variation) is a fundamental prerequisite for evolution by natural selection. It is the living organism as a whole that contributes (or not) to the next generation, so natural selection affects the genetic structure of a population indirectly via the contribution of phenotypes. Without phenotypic variation, there would be no evolution by natural selection.
The interaction between genotype and phenotype has often been conceptualized by the following relationship:
genotype + environment → phenotype
A slightly more nuanced version of the relationships is:
genotype + environment + random-variation → phenotype
An example of random variation in Drosophila flies is the number of ommatidia, which may vary (randomly) between left and right eyes in a single individual as much as they do between different genotypes overall, or between clones raised in different environments.
A phenotype is any detectable characteristic of an organism (i.e., structural, biochemical, physiological, and behavioral) determined by an interaction between its genotype and environment (of this distinction).
According to the autopoietic notion of living systems by Humberto Maturana, the phenotype is epigenetically being constructed throughout ontogeny, and we as observers make the distinctions that define any particular trait at any particular state of the organism's life cycle.
The idea of the phenotype has been generalized by Richard Dawkins in The Extended Phenotype to mean all the effects a gene has on the outside world that may influence its chances of being replicated. These can be effects on the organism in which the gene resides, the environment, or other organisms. For instance, a beaver dam might be considered a phenotype of beaver genes, the same way beaver's powerful incisor teeth are phenotype expressions of their genes.
The concept of phenotype can be extended to variations below the level of the gene that affect an organism's fitness. For example, silent mutations that do not change the corresponding amino acid sequence of a gene may change the frequency of guanine-cytosine base pairs (GC content). These base pairs have a higher thermal stability (melting point, see also DNA-DNA hybridization) than adenine-thymine, a property that might convey, among organisms living in high-temperature environments, a selective advantage on variants enriched in GC content.


See also

phenotypic in Arabic: نمط ظاهري
phenotypic in Bulgarian: Фенотип
phenotypic in Catalan: Fenotip
phenotypic in Czech: Fenotyp
phenotypic in Danish: Fænotype
phenotypic in German: Phänotyp
phenotypic in Estonian: Fenotüüp
phenotypic in Spanish: Fenotipo
phenotypic in Esperanto: Fenotipo
phenotypic in French: Phénotype
phenotypic in Galician: Fenotipo
phenotypic in Korean: 발현형질
phenotypic in Ido: Fenotipo
phenotypic in Indonesian: Fenotipe
phenotypic in Italian: Fenotipo
phenotypic in Hebrew: גן (ביולוגיה)#.D7.9E.D7.95.D7.A9.D7.92.D7.99.D7.9D_.D7.91.D7.A1.D7.99.D7.A1.D7.99.D7.99.D7.9D
phenotypic in Hungarian: Fenotípus
phenotypic in Macedonian: Фенотип
phenotypic in Dutch: Fenotype
phenotypic in Japanese: 表現型
phenotypic in Polish: Fenotyp
phenotypic in Portuguese: Fenótipo
phenotypic in Romanian: Fenotip
phenotypic in Russian: Фенотип
phenotypic in Simple English: Phenotype
phenotypic in Slovak: Fenotyp
phenotypic in Serbian: Фенотип
phenotypic in Finnish: Fenotyyppi
phenotypic in Swedish: Fenotyp
phenotypic in Turkish: Fenotip
phenotypic in Ukrainian: Фенотип
phenotypic in Chinese: 表現型
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